Reserach Technician: Molecular technology development

60%-100%, Basel, fixed-term

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The Laboratory for Biological Engineering (Prof. Randall J Platt) of the ETH Zurich in Basel, Switzerland develops genome engineering technologies and applies them to a range of fundamental and disease-focused areas. To advance these efforts, the Platt group is recruiting a part- (at least 60%) or full-time (100%) research technician to support ongoing experimental efforts.

Project background

We are looking for a research technician to work with scientists in the laboratory on their ongoing projects related to molecular technology development, CRISPR technologies, pooled screening, viral vectors, and mouse models.

Job description

We are looking for a highly organized research technician to join a multidisciplinary team of researchers. The candidate will work closely with laboratory members to aid in planning and running experiments.

Research technican duties primarily include:

• molecular cloning (PCR, classic restriction enzyme cloning, Golden-Gate Assembly and Gibson assembly)
• preparation of plasmid DNA from E. coli
• maintenance and transfection of standard mammalian cell lines
• flow cytometry
• production and purification of lentivirus and adeno-associated virus
• titration of these respective viruses by functional titration, qPCR or droplet digital PCR
• preparation of DNA libraries for high-throughput sequencing
• other common tasks of molecular and cellular biology

Research technician duties may also involve mouse models, including husbandry, injections, tissue dissection, and cell or nuclei isolation.

Profile

The ideal candidate will have at least completed the apprenticeship for a biology laboratory techician OR a Master-s degree or equivalent in Molecular Biotechnology, Biochemistry, Molecular Medicine, Structural Biology, Molecular and Cellular Biology, or a related field.

The candidate must be able to communicate effectively in a highly interdisciplinary and international environment, which includes a mastery of oral and written English. The candidate will be passionate about science, technology, collaboration, and communication. The candidate must have a strong motivation and interest in collaboration with multi-disciplinary scientists.

Extensive prior experience with contemporary methods in molecular and cellular biology, including the duties listed above, is essential. Mastery of Excel, Powerpoint, and at least one cloning (e.g., Geneious) and plotting (e.g., Prism) software is essential. Prior experience with illustration software (e.g., Adobe Illustrator, BioRender) is not essential but a major plus. Prior experience with mouse models is not essential but a major plus.

Workplace

Workplace

We offer

The position is located in the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel, Switzerland. The D-BSSE is a highly interdisciplinary department - specializing in systems and synthetic biology, bioinformatics and data science, and engineering sciences related to microfluidics and microfabrication. The D-BSSE is centrally located within a biomedical research hub with close links to top academic institutions (e.g., Friedrich Miescher Institute (FMI), Biozentrum and University of Basel) as well as major biotechnology and pharmaceutical companies (e.g., Novartis, Roche, Bayer, and Lonza). The ETH Zurich is a global leader in science and technology and consistently ranks as one of the top universities in the world. Basel, Switzerland is an international city on the border with France and Germany - nested between the Swiss alps, black forest, and cheese and wine country. The city provides easy access to arts and culture, nature and adventure, and short commutes via train/plain/automobile to anywhere in Europe.

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We value diversity

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish.

Curious? So are we.

We look forward to receiving your online application with the following documents:

• Cover letter that contextualizes your scientific background, skills, and interests as well as articulates why you are interested in the group
• CV
• Diplomas and course transcripts
• Contact details of at least two referees

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Further information about Department of Biosystems Science and Engineering (D-BSSE) can be found on our website. Questions regarding the position should be directed to Prof. Platt (rplatt@ethz.ch) (no applications).

About ETH Zürich

ETH Zurich is one of the world-s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.