Postdoctoral researcher in T cell engineering and immuno-oncology

Contexte

The Lausanne University Hospital (CHUV) is one of five Swiss university hospitals. Through its collaboration with the Faculty of Biology and Medicine of the University of Lausanne and the EPFL, CHUV plays a leading role in the areas of medical care, medical research and training.

The Department of Oncology UNIL-CHUV brings together clinical and cancer research in a strong spirit of innovation. It comprises the services of medical oncology, immuno-oncology including advanced cellular therapies, radiation oncology, hematology including stem cell transplantation and the center for experimental therapies. It also integrates the Lausanne branch of the Ludwig Institute for Cancer Research (LICR), particularly in the field of immunotherapy.

Mission

You will work on a translational project investigating chimeric antigen receptor (CAR) T cells and other adoptive cell therapies, primarily through advanced microscopy approaches. Your responsibilities will include :

• Visualizing the dynamics and nanoscale structure of immune synapses between engineered T cells and tumor cells
• Investigating how different CAR constructs affect target cell killing
• Actively contributing to internal presentations, departmental seminars, and scientific conferences
• Assisting with the preparation of scientific publications, reports, and grant applications (in English)
• Supporting the supervision of Master’s and PhD students and lab technicians.

What we offer

• Close mentoring and teaching in advanced imaging techniques, including cryo-expansion microscopy, dSTORM, and live cell microscopy, with direct applications in translational immune-oncology, T cell engineering, and cell therapy manufacturing
• A collaborative and supportive lab culture that values intellectual exchange, creativity, and autonomy
• Participation in national and international scientific conferences
• High quality of life in Lausanne, one of Switzerland’s most vibrant academic and cultural hubs.

Profil

• PhD (or equivalent) in Physics, Biology, Biochemistry, Cancer Immunology, or a related field
• Proven experience in cell culture techniques
• Solid background in immunofluorescence and fluorescence microscopy
• Familiarity with automated image analysis workflows
• Prior experience in human immunology and lymphocyte engineering is a strong asset
• Keen interest in translational immune-oncology (experience is a plus but not required)
• Proficiency in flow cytometry and standard computational tools
• Fluent in English (spoken and written), including scientific communication
• Adaptable, self-motivated, and comfortable in a dynamic research environmen.
  

To apply, please send your application as a single PDF including :

• A brief motivation letter
• Your CV
• A list of publications, and
• Contact details of two referees.

Nous offrons

To become an employee of the world-famous University Hospital Center from the Canton of Vaud is an assurance of :

• First-rate social benefits such as a Paternity Leave of 20 days and a Maternity Leave of 4 months (there is also the possibility to obtain a complementary breastfeeding leave of 1 month)
• Regular salary progression adapted to your responsibilities
• A 13th salary and 25 days of vacations per year
• A right to at least three days of training per year, by accessing a wide offer of courses not only from the CHUV Training Center but also from external providers
• Possibility to access one of the 500 furnished apartments offered in the surrounding neighborhoods in case of relocation in Switzerland
• Discounts proposed on social and cultural events, goodies and other services, thanks to the “H-Oxygène” association
• Signing up to our Mobility Plan and benefit from different advantages (discounts on public transportation, promotion of “Mobility” car fleet and discounts on electric bikes)
• Being able to enjoy our high-quality corporate restaurants, located in every hospital building, with employees’ discount.

Contact et envoi de candidature

Contact person in case of questions about this role : Dr Benita Wolf, MD, Attending Physician, Department of oncology UNIL-CHUV - Ludwig Institute for Cancer Research Lausanne,

All of our applications are processed electronically. For this reason, we kindly ask you to apply exclusively by clicking on the APPLY button at the bottom of the advertisement.

Should you experience any problems with your application, you can consult our document "". In case of technical issues, you can contact our Recruitment team who will help you ( / +41 21 314 85 70). 

The CHUV applies the highest quality requirements as part of its recruitment process. In addition, mindful to promote workplace diversity and inclusion we strive to ensure equal treatment and avoid any discrimination. We are looking forward to receiving your application.

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